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Tbio
RAVER2
Ribonucleoprotein PTB-binding 2

Protein Summary
Description
May bind single-stranded nucleic acids.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000294428
  • ENSP00000294428
  • ENSG00000162437
  • ENST00000371072
  • ENSP00000360112

Symbol
  • KIAA1579
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.77
histone modification site profile
0.71
cell type or tissue
0.69
tissue sample
0.68
cell line
0.49


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.97   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 64   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.97   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 64   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (24)
SPATA20
Tdark
Novelty:  0.34126403
p_int:  0.999999818
p_ni:  1.81e-7
p_wrong:  1e-9
Score:  0.235
Data Source:  BioPlex,STRINGDB
QPRT
Tbio
Family:  Enzyme
Novelty:  0.00781554
p_int:  0.999999217
p_ni:  7.77e-7
p_wrong:  6e-9
Score:  0.212
Data Source:  BioPlex,STRINGDB
TIMM8A
Tbio
Family:  Enzyme
Novelty:  0.00954602
p_int:  0.999991216
p_ni:  0.000008777
p_wrong:  7e-9
Data Source:  BioPlex
HNRNPLL
Tbio
Novelty:  0.0498467
p_int:  0.998877814
p_ni:  0.000015856
p_wrong:  0.00110633
Data Source:  BioPlex
PTBP1
Tbio
Novelty:  0.00184728
Score:  0.765
Data Source:  STRINGDB
PTBP3
Tbio
Novelty:  0.02001829
Score:  0.683
Data Source:  STRINGDB
HNRNPDL
Tbio
Novelty:  0.00222179
Score:  0.629
Data Source:  STRINGDB
HNRNPC
Tbio
Novelty:  0.00136097
Score:  0.6
Data Source:  STRINGDB
KHSRP
Tbio
Novelty:  0.01131549
Score:  0.586
Data Source:  STRINGDB
KHDRBS2
Tbio
Novelty:  0.01986638
Score:  0.514
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
C-reactive protein measurement
1
3
3
78.6
eosinophil count
2
2
2
74.8
eosinophil percentage of leukocytes
1
1
1
63.7
alkaline phosphatase measurement
1
1
1
61.4
sum of eosinophil and basophil counts
1
1
1
48.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
C-reactive protein measurement
3
78.6
eosinophil count
2
74.8
eosinophil percentage of leukocytes
1
63.7
alkaline phosphatase measurement
1
61.4
sum of eosinophil and basophil counts
1
48.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ribonucleoprotein, PTB binding 2
VGNC:10033
469344
Macaque
ribonucleoprotein, PTB binding 2
701724
Mouse
MGI:2443623
242570
Rat
RGD:1307610
362551
Dog
ribonucleoprotein, PTB binding 2
VGNC:45387
489556
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ribonucleoprotein, PTB binding 2
Macaque
ribonucleoprotein, PTB binding 2
Mouse
Rat
Dog
ribonucleoprotein, PTB binding 2
Publication Statistics
PubMed Score 3.97
PubMed score by year
PubTator Score 2.08
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title