Protein Summary
May function in nuclear protein import as nuclear transport receptor.
- ENST00000259569
- ENSP00000259569
- ENSG00000137040
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
interacting protein | 0.85 | ||
histone modification site profile | 0.73 | ||
transcription factor binding site profile | 0.67 | ||
cell type or tissue | 0.63 | ||
cell line | 0.61 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.86 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 95 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.86 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 95 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (130)
ATP9A
Family: Transporter
Novelty: 0.15755352
p_int: 0.999999391
p_ni: 6.08e-7
Data Source: BioPlex
STEAP3
Family: Enzyme
Novelty: 0.02042104
p_int: 0.999958589
p_ni: 0.000041408
p_wrong: 4e-9
Data Source: BioPlex
ATP2B3
Family: Transporter
Novelty: 0.00901493
p_int: 0.99978019
p_ni: 0.00021981
Score: 0.164
Data Source: BioPlex,STRINGDB
SLC27A2
Family: Transporter
Novelty: 0.01436035
p_int: 0.999706887
p_ni: 0.000293113
Data Source: BioPlex
C3orf33
Novelty: 0.29931973
p_int: 0.999654147
p_ni: 0.000345811
p_wrong: 4.2e-8
Data Source: BioPlex
EXOG
Family: Enzyme
Novelty: 0.03588463
p_int: 0.996846851
p_ni: 0.003153133
p_wrong: 1.6e-8
Score: 0.193
Data Source: BioPlex,STRINGDB
TYW1B
Family: Enzyme
Novelty: 0.86504466
p_int: 0.995902228
p_ni: 0.004047112
p_wrong: 0.00005066
Score: 0.253
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (6)
Functions (1)
Components (3)
Processes (2)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Disease Associations ()
GWAS Traits (10)
Items per page:
1 – 5 of 10
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
4 | 4 | 0 | 1.1 | 92.3 | |||||
age at onset | 1 | 2 | 0 | 1.1 | 62.5 | ||||
glycine measurement | 3 | 1 | 3 | 38.1 | |||||
childhood onset asthma | 1 | 1 | 0 | 1.2 | 35 | ||||
adult onset asthma | 1 | 1 | 0 | 1.1 | 21 | ||||
Items per page:
1 – 5 of 10
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
0 | 1.1 | 92.3 | |||||
age at onset | 0 | 1.1 | 62.5 | ||||
glycine measurement | 3 | 38.1 | |||||
childhood onset asthma | 0 | 1.2 | 35 | ||||
adult onset asthma | 0 | 1.1 | 21 | ||||
Find similar targets by:
IDG Resources
Orthologs (6)
1 – 5 of 6
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Mouse | MGI:2683212 | 240614 | ||||||
Rat | RGD:1305165 | 309326 | ||||||
Horse | RAN binding protein 6 | VGNC:22173 | 100059812 | |||||
Cow | RAN binding protein 6 | VGNC:50254 | 526705 | |||||
C. elegans | 3565440 | |||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Horse | RAN binding protein 6 | |||||
Cow | RAN binding protein 6 | |||||
C. elegans | ||||||
Publication Statistics
PubMed Score 0.86
PubMed score by year
PubTator Score 1.88
PubTator score by year
Related Publications
Text Mined References (10)
GeneRif Annotations (2)
Items per page:
0 of 0
PMID | Year | Title |
|---|