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Tbio
RALGPS1
Ras-specific guanine nucleotide-releasing factor RalGPS1

Protein Summary
Description
Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000259351
  • ENSP00000259351
  • ENSG00000136828
  • ENST00000373434
  • ENSP00000362533
  • ENST00000373436
  • ENSP00000362535
  • ENST00000394011
  • ENSP00000377579
  • ENST00000394022
  • ENSP00000377590
  • ENST00000424082
  • ENSP00000415630

Symbol
  • KIAA0351
  • RALGEF2
  • RALGEF2
  • RALGPS1A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.97
virus perturbation
0.88
kinase perturbation
0.76
transcription factor
0.61
transcription factor perturbation
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.17   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 63   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.17   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 63   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0