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Tbio
RALGAPB
Ral GTPase-activating protein subunit beta

Protein Summary
Description
Non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes which act as GTPase activators for the Ras-like small GTPases RALA and RALB.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000262879
  • ENSP00000262879
  • ENSG00000170471
  • ENST00000397040
  • ENSP00000380233
  • ENST00000397042
  • ENSP00000380235

Symbol
  • KIAA1219
  • KIAA1219
  • RalGAPbeta
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.95
microRNA
0.82
kinase perturbation
0.81
histone modification site profile
0.74
transcription factor binding site profile
0.73


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.33   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 22   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.33   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0