Tbio RADIL Ras-associating and dilute domain-containing protein

Protein Summary

Description

Downstream effector of Rap required for cell adhesion and migration of neural crest precursors during development.

Uniprot Accession IDs

• Q96JH8
• A4D1Z5
• A5YM49
• B7ZL20
• Q0VFZ9
• Q75LH3
• Q9BSP5
• Q9H0M6
• Q9NW43
• Q9NWC4

Gene Name

• RADIL

Ensembl ID

• ENST00000399583
• ENSP00000382492
• ENSG00000157927

Symbol

• KIAA1849
• RASIP2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.92
cell type or tissue	0.69
gene perturbation	0.65
transcription factor binding site profile	0.62
transcription factor	0.58

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.28   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 137   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.28   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 137   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0