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Tdark
RAD9B
Cell cycle checkpoint control protein RAD9B

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.81   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 65   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.81   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 65   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (85)
YEATS2
Tbio
Novelty:  0.17584498
p_int:  0.985059022
p_ni:  0.014940977
p_wrong:  1e-9
Data Source:  BioPlex
ZZZ3
Tdark
Family:  TF
Novelty:  0.23862921
p_int:  0.980293948
p_ni:  0.019706048
p_wrong:  4e-9
Data Source:  BioPlex
KAT14
Tbio
Novelty:  0.17168043
p_int:  0.963242432
p_ni:  0.036757568
Data Source:  BioPlex
FAM208A
Tbio
Novelty:  0.17789689
p_int:  0.954844575
p_ni:  0.045155425
Data Source:  BioPlex
TPP2
Tchem
Family:  Enzyme
Novelty:  0.00803674
p_int:  0.953303888
p_ni:  0.045508519
p_wrong:  0.001187593
Data Source:  BioPlex
TTF2
Tbio
Novelty:  0.20281859
p_int:  0.924907178
p_ni:  0.075092822
Data Source:  BioPlex
TBC1D4
Tbio
Novelty:  0.00549202
p_int:  0.879716972
p_ni:  0.120283028
Data Source:  BioPlex
LRIF1
Tdark
Novelty:  0.26861958
p_int:  0.825706541
p_ni:  0.122428768
p_wrong:  0.05186469
Data Source:  BioPlex
RAD21
Tbio
Novelty:  0.00270936
p_int:  0.820060722
p_ni:  0.179935324
p_wrong:  0.000003954
Data Source:  BioPlex
BBS1
Tbio
Novelty:  0.00939439
p_int:  0.79950674
p_ni:  0.20049326
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (42)
Activation of ATR in response to replication stress (R-HSA-176187)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 20
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Activation of ATR in response to replication stress
Reactome
Cell Cycle
Reactome
Cell Cycle Checkpoints
Reactome
DNA Double-Strand Break Repair
Reactome
DNA Repair
Name
Explore in Pharos
Explore in Source
Activation of ATR in response to replication stress
Cell Cycle
Cell Cycle Checkpoints
DNA Double-Strand Break Repair
DNA Repair
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
2
1
2
71.3
body height
1
1
1
48.5
risk-taking behaviour
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
2
71.3
body height
1
48.5
risk-taking behaviour
1
21.5
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
RAD9 checkpoint clamp component B
VGNC:5564
452238
Macaque
RAD9 checkpoint clamp component B
711050
Mouse
MGI:2385231
231724
Rat
RGD:1308223
363924
Dog
RAD9 checkpoint clamp component B
VGNC:45323
100855506
Species
Name
OMA
EggNOG
Inparanoid
Chimp
RAD9 checkpoint clamp component B
Macaque
RAD9 checkpoint clamp component B
Mouse
Rat
Dog
RAD9 checkpoint clamp component B
Publication Statistics
PubMed Score 2.81
PubMed score by year
PubTator Score 1.22
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title