Tbio RAB6B Ras-related protein Rab-6B

Protein Summary

Description

Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.

Uniprot Accession IDs

• Q9NRW1
• B2R5Z9
• B7Z337
• D3DND3
• Q92929

Gene Name

• RAB6B

Ensembl ID

• ENST00000285208
• ENSP00000285208
• ENSG00000154917
• ENST00000486858
• ENSP00000419381
• ENST00000543906
• ENSP00000437797

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.95
kinase perturbation	0.84
transcription factor perturbation	0.84
PubMedID	0.79
gene perturbation	0.75

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.91   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 166   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.91   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 166   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0