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Tbio
RAB3A
Ras-related protein Rab-3A

Protein Summary
Description
Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000222256
  • ENSP00000222256
  • ENSG00000105649
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.99
cellular component
0.91
biological process
0.9
histone modification site profile
0.89
small molecule perturbation
0.77


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 238.47   (req: < 5)
Gene RIFs: 20   (req: <= 3)
Antibodies: 322   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 238.47   (req: >= 5)
Gene RIFs: 20   (req: > 3)
Antibodies: 322   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 35
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0