Tbio RAB3A Ras-related protein Rab-3A

Protein Summary

Description

Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.

Uniprot Accession IDs

• P20336
• A8K0J4
• Q9NYE1

Gene Name

• RAB3A

Ensembl ID

• ENST00000222256
• ENSP00000222256
• ENSG00000105649

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.99
cellular component	0.91
biological process	0.9
histone modification site profile	0.89
small molecule perturbation	0.77

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 238.47   (req: < 5)

Gene RIFs: 19   (req: <= 3)

Antibodies: 322   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 238.47   (req: >= 5)

Gene RIFs: 19   (req: > 3)

Antibodies: 322   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 35

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0