Tbio RAB37 Ras-related protein Rab-37

Protein Summary

Description

Rab proteins are low molecular mass GTPases that are critical regulators of vesicle trafficking. For additional background information on Rab proteins, see MIM 179508.[supplied by OMIM, Apr 2006]

Uniprot Accession IDs

• Q96AX2
• A8MXF5
• A8MYT0
• Q8IWA7

Gene Name

• RAB37

Ensembl ID

• ENST00000392612
• ENSP00000376388
• ENSG00000172794
• ENST00000392613
• ENSP00000376389
• ENST00000392614
• ENSP00000376390
• ENST00000402449
• ENSP00000383934
• ENST00000481224
• ENSP00000436563
• ENST00000613645
• ENSP00000483155

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.91
kinase perturbation	0.76
gene perturbation	0.74
transcription factor	0.71
interacting protein	0.65

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.09   (req: < 5)

Gene RIFs: 13   (req: <= 3)

Antibodies: 316   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.09   (req: >= 5)

Gene RIFs: 13   (req: > 3)

Antibodies: 316   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0