RAB2B
Ras-related protein Rab-2B
Protein Summary
Required for protein transport from the endoplasmic reticulum to the Golgi complex. Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006]
- ENST00000397762
- ENSP00000380869
- ENSG00000129472
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor perturbation | 0.94 | ||
histone modification site profile | 0.91 | ||
kinase perturbation | 0.91 | ||
molecular function | 0.91 | ||
virus perturbation | 0.88 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 6.57 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 193 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 6.57 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 193 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0