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Tdark
R3HDM1
R3H domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000264160
  • ENSP00000264160
  • ENSG00000048991
  • ENST00000409478
  • ENSP00000386457
  • ENST00000409606
  • ENSP00000387010
  • ENST00000410054
  • ENSP00000386877
  • ENST00000628915
  • ENSP00000486837

Symbol
  • KIAA0029
  • R3HDM
  • R3HDM
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.91
histone modification site profile
0.85
co-expressed gene
0.72
transcription factor
0.68
virus perturbation
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.82   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 10   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.82   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 10   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (27)
LITAF
Tbio
Family:  TF
Novelty:  0.0097203
p_int:  0.999997941
p_ni:  0.000001718
p_wrong:  3.41e-7
Score:  0.232
Data Source:  BioPlex,STRINGDB
TCL1A
Tbio
Novelty:  0.00606987
p_int:  0.998589643
p_ni:  0.000044351
p_wrong:  0.001366006
Data Source:  BioPlex
WDYHV1
Tbio
Family:  Enzyme
Novelty:  0.1844203
p_int:  0.967951257
p_ni:  0.000002019
p_wrong:  0.032046725
Score:  0.189
Data Source:  BioPlex,STRINGDB
ZRANB3
Tbio
Family:  Enzyme
Novelty:  0.00398767
Score:  0.644
Data Source:  STRINGDB
COPZ2
Tdark
Novelty:  0.21561497
Score:  0.616
Data Source:  STRINGDB
RAB3GAP1
Tbio
Family:  Enzyme
Novelty:  0.0286836
Score:  0.546
Data Source:  STRINGDB
MAP3K19
Tchem
Family:  Kinase
Novelty:  0.27091951
Score:  0.512
Data Source:  STRINGDB
LRRFIP2
Tbio
Novelty:  0.15492934
Score:  0.51
Data Source:  STRINGDB
TMEM163
Tbio
Novelty:  0.04613489
Score:  0.507
Data Source:  STRINGDB
LMBRD1
Tbio
Novelty:  0.02503332
Score:  0.5
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
gut microbiome measurement
5
7
0
6.4
90.3
apolipoprotein A 1 measurement
1
1
1
67.1
high density lipoprotein cholesterol measurement
1
1
1
62.1
red blood cell distribution width
2
2
2
57.7
grip strength measurement
2
1
2
54.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
gut microbiome measurement
0
6.4
90.3
apolipoprotein A 1 measurement
1
67.1
high density lipoprotein cholesterol measurement
1
62.1
red blood cell distribution width
2
57.7
grip strength measurement
2
54.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
R3H domain containing 1
VGNC:2794
459631
Macaque
R3H domain containing 1
707987
Mouse
MGI:2448514
226412
Rat
RGD:1307497
304763
Dog
R3H domain containing 1
VGNC:45244
476129
Species
Name
OMA
EggNOG
Inparanoid
Chimp
R3H domain containing 1
Macaque
R3H domain containing 1
Mouse
Rat
Dog
R3H domain containing 1
Publication Statistics
PubMed Score 5.82
PubMed score by year
PubTator Score 2.50
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title