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Tbio
ZFP37
Zinc finger protein 37 homolog

Protein Summary
Description
May be involved in transcriptional regulation. This gene encodes a transcription factor that belongs to a large family of zinc finger proteins. A similar protein in mouse is thought to play a role in regulating the structures of the nucleolus and centromere in neurons. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000374227
  • ENSP00000363344
  • ENSG00000136866
  • ENST00000553380
  • ENSP00000452552
  • ENST00000555206
  • ENSP00000451310

Symbol
  • ZNF906
  • zfp-37
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.83
protein domain
0.58
tissue
0.52
transcription factor binding site profile
0.5
virus perturbation
0.5


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.57   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 67   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.57   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 67   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ZFP37 zinc finger protein
VGNC:8953
473025
Macaque
ZFP37 zinc finger protein
710438
Mouse
MGI:99181
22696
Rat
Dog
ZFP37 zinc finger protein
VGNC:49667
111089991
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ZFP37 zinc finger protein
Macaque
ZFP37 zinc finger protein
Mouse
Rat
Dog
ZFP37 zinc finger protein
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9Y6Q3-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (28)
1 – 10 of 28
WDR46
Tbio
Novelty: 0.19307408
p_int: 0.995999898
p_ni: 0.000003146
p_wrong: 0.003996956
Score: 0.189
Data Source: BioPlex,STRINGDB
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.903
Data Source: STRINGDB
SLC46A2
Tdark
Family: Transporter
Novelty: 0.12003352
Score: 0.754
Data Source: STRINGDB
FHIT
Tchem
Family: Enzyme
Novelty: 0.0012803
Score: 0.712
Data Source: STRINGDB
COP1
Tbio
Family: Enzyme
Novelty: 0.10908534
Score: 0.688
Data Source: STRINGDB
FKBP15
Tbio
Novelty: 0.0570695
Score: 0.669
Data Source: STRINGDB
BRINP2
Tdark
Novelty: 0.5101917
Score: 0.654
Data Source: STRINGDB
TAF11
Tbio
Novelty: 0.10299251
Score: 0.644
Data Source: STRINGDB
SF3B4
Tbio
Novelty: 0.0197008
Score: 0.643
Data Source: STRINGDB
TMEM62
Tdark
Novelty: 1.79070108
Score: 0.627
Data Source: STRINGDB
Publication Statistics
PubMed Score  8.57

PubMed score by year
PubTator Score  2.19

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer