SLCO1B1
Solute carrier organic anion transporter family member 1B1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
drug | 1 | ||
biological term | 0.9 | ||
chemical | 0.86 | ||
disease | 0.8 | ||
phenotype | 0.62 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Bile acid and bile salt metabolism | ||||
Reactome | Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR) | ||||
Reactome | Disease | ||||
Reactome | Disorders of transmembrane transporters | ||||
Reactome | Metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Bile acid and bile salt metabolism | ||||
Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR) | ||||
Disease | ||||
Disorders of transmembrane transporters | ||||
Metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | Reactome | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
bilirubin measurement | 6 | 14 | 24 | 99.9 | |||||
blood metabolite measurement | 2 | 4 | 14 | 98.8 | |||||
sex hormone-binding globulin measurement | 7 | 3 | 7 | 97.8 | |||||
serum metabolite measurement | 1 | 3 | 10 | 97.2 | |||||
testosterone measurement | 4 | 2 | 4 | 91.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
bilirubin measurement | 24 | 99.9 | |||||
blood metabolite measurement | 14 | 98.8 | |||||
sex hormone-binding globulin measurement | 7 | 97.8 | |||||
serum metabolite measurement | 10 | 97.2 | |||||
testosterone measurement | 4 | 91.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | solute carrier organic anion transporter family member 1B1 | VGNC:8551 | 465331 | |||||
Macaque | solute carrier organic anion transporter family member 1B1 | 705308 | ||||||
Dog | solute carrier organic anion transporter family member 1B3 | 403519 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | solute carrier organic anion transporter family member 1B1 | |||||
Macaque | solute carrier organic anion transporter family member 1B1 | |||||
Dog | solute carrier organic anion transporter family member 1B3 | |||||
PMID | Year | Title |
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