DNMT3A
DNA (cytosine-5)-methyltransferase 3A
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological term | 0.95 | ||
transcription factor | 0.93 | ||
transcription factor binding site profile | 0.92 | ||
PubMedID | 0.9 | ||
transcription factor perturbation | 0.88 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Chromatin modifying enzymes | ||||
Reactome | Chromatin organization | ||||
Reactome | DNA methylation | ||||
Reactome | Epigenetic regulation of gene expression | ||||
Reactome | Gene expression (Transcription) | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Chromatin modifying enzymes | ||||
Chromatin organization | ||||
DNA methylation | ||||
Epigenetic regulation of gene expression | ||||
Gene expression (Transcription) | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted waist circumference | 6 | 19 | 26 | 96.2 | |||||
body height | 3 | 2 | 3 | 91.5 | |||||
neutrophil percentage of leukocytes | 2 | 3 | 3 | 91.2 | |||||
BMI-adjusted hip circumference | 2 | 9 | 10 | 91.2 | |||||
BMI-adjusted waist-hip ratio | 4 | 8 | 9 | 90.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted waist circumference | 26 | 96.2 | |||||
body height | 3 | 91.5 | |||||
neutrophil percentage of leukocytes | 3 | 91.2 | |||||
BMI-adjusted hip circumference | 10 | 91.2 | |||||
BMI-adjusted waist-hip ratio | 9 | 90.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | DNA methyltransferase 3 alpha | VGNC:219 | 739139 | |||||
Macaque | DNA methyltransferase 3 alpha | 694822 | ||||||
Mouse | MGI:1261827 | 13435 | ||||||
Rat | RGD:1303336 | 444984 | ||||||
Dog | DNA methyltransferase 3 alpha | VGNC:40036 | 482996 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | DNA methyltransferase 3 alpha | |||||
Macaque | DNA methyltransferase 3 alpha | |||||
Mouse | ||||||
Rat | ||||||
Dog | DNA methyltransferase 3 alpha | |||||
PMID | Year | Title |
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