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Tdark
TEX264
Testis-expressed protein 264

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000341333
  • ENSP00000340969
  • ENSG00000164081
  • ENST00000395057
  • ENSP00000378497
  • ENST00000415259
  • ENSP00000396628
  • ENST00000416589
  • ENSP00000398802
  • ENST00000457573
  • ENSP00000408186
  • ENST00000611400
  • ENSP00000477946

Symbol
  • ZSIG11
  • ZSIG11
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.85
histone modification site profile
0.74
drug perturbation
0.71
kinase perturbation
0.71
transcription factor
0.7


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.41   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 83   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.41   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 83   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
1
1
1
63.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
1
63.4
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
testis expressed 264
700350
Mouse
MGI:1096570
21767
Rat
RGD:1359353
300988
Dog
testis expressed 264
VGNC:47271
476607
Horse
testis expressed 264
VGNC:24017
100147234
Species
Name
OMA
EggNOG
Inparanoid
Macaque
testis expressed 264
Mouse
Rat
Dog
testis expressed 264
Horse
testis expressed 264
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9Y6I9-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Hemostasis (R-HSA-109582)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Hemostasis
Reactome
Platelet activation, signaling and aggregation
Reactome
Platelet degranulation
Reactome
Response to elevated platelet cytosolic Ca2+
Name
Explore in Pharos
Explore in Source
Hemostasis
Platelet activation, signaling and aggregation
Platelet degranulation
Response to elevated platelet cytosolic Ca2+
Gene Ontology Terms (3)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
Reactome
Traceable Author Statement (TAS)
Reactome
Protein-Protein Interactions (127)
1 – 10 of 127
MINK1
Tchem
Family: Kinase
Novelty: 0.00505208
p_int: 0.999988068
p_ni: 0.000004114
p_wrong: 0.000007818
Score: 0.161
Data Source: BioPlex,STRINGDB
POTEI
Tdark
Novelty: 0.41311202
p_int: 0.999950156
p_ni: 0.000049843
p_wrong: 1e-9
Data Source: BioPlex
ENTPD7
Tbio
Family: Enzyme
Novelty: 0.1810079
p_int: 0.999897782
p_ni: 0.000102218
Data Source: BioPlex
CHEK2
Tchem
Family: Kinase
Novelty: 0.00068355
p_int: 0.999520319
p_ni: 0.000040482
p_wrong: 0.000439199
Score: 0.224
Data Source: BioPlex,STRINGDB
PLD1
Tchem
Family: Enzyme
Novelty: 0.00608142
p_int: 0.997242649
p_ni: 0.002757351
Data Source: BioPlex
C1orf43
Tbio
Novelty: 0.13587458
p_int: 0.995729305
p_ni: 0.004270692
p_wrong: 3e-9
Data Source: BioPlex
CEP131
Tbio
Novelty: 0.02562073
p_int: 0.993672934
p_ni: 0.006202311
p_wrong: 0.000124754
Data Source: BioPlex
MCM10
Tbio
Novelty: 0.0136058
p_int: 0.977193269
p_ni: 0.022805283
p_wrong: 0.000001449
Data Source: BioPlex
ABCC10
Tbio
Family: Transporter
Novelty: 0.02281831
p_int: 0.974809458
p_ni: 0.023764129
p_wrong: 0.001426413
Score: 0.183
Data Source: BioPlex,STRINGDB
EDA
Tbio
Novelty: 0.00352464
p_int: 0.973022945
p_ni: 0.026977055
Data Source: BioPlex
Publication Statistics
PubMed Score  4.41

PubMed score by year
PubTator Score  0.07

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer