CDY2A
Testis-specific chromodomain protein Y 2
Protein Summary
May have histone acetyltransferase activity. This intronless gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. Two nearly identical copies of this gene are found in a palindromic region on chromosome Y; this record represents the centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. [provided by RefSeq, Jul 2008]
- ENST00000250838
- ENSP00000250838
- ENSG00000182415
- ENST00000382867
- ENSP00000372319
- ENSG00000129873
- CDY2
- CDY
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
virus perturbation | 0.55 | ||
metabolite | 0.45 | ||
protein complex | 0.4 | ||
disease | 0.35 | ||
biological term | 0.33 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 37 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 37 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0