Protein Summary
Transcription repressor involved in the exit of embryonic stem cells (ESCs) from self-renewal. Acts by repressing expression of KLF4.
- ENST00000311212
- ENSP00000311768
- ENSG00000120963
- ENST00000517844
- ENSP00000428227
- ENST00000518336
- ENSP00000428696
- ENST00000519882
- ENSP00000428985
- ENST00000520347
- ENSP00000430823
- ENST00000520984
- ENSP00000427761
- ENST00000521272
- ENSP00000430165
- HSPC038
- PNAS-106
- PNAS-113
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
disease perturbation | 1 | ||
transcription factor perturbation | 1 | ||
transcription factor binding site profile | 0.97 | ||
histone modification site profile | 0.86 | ||
virus perturbation | 0.76 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 4.1 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 36 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 4.1 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 36 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (34)
SP100
Family: TF; Epigenetic
Novelty: 0.00201806
p_int: 0.819381864
p_ni: 0.000017075
p_wrong: 0.180601061
Score: 0.692
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (3)
Reactome (3)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | RNA Polymerase II Transcription | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
RNA Polymerase II Transcription | ||||
Viral Interactions (0)
Gene Ontology Terms (6)
Functions (1)
Components (2)
Processes (3)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations ()
GWAS Traits (0)
Find similar targets by:
IDG Resources
Orthologs (11)
1 – 5 of 11
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Macaque | zinc finger protein 706 | 710457 | ||||||
Mouse | MGI:1915286 | 68036 | ||||||
Dog | zinc finger protein 706 | VGNC:48804 | 607293 | |||||
Horse | zinc finger protein 706 | VGNC:25378 | 100629307 | |||||
Cow | zinc finger protein 706 | VGNC:37336 | 614279 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Macaque | zinc finger protein 706 | |||||
Mouse | ||||||
Dog | zinc finger protein 706 | |||||
Horse | zinc finger protein 706 | |||||
Cow | zinc finger protein 706 | |||||
Publication Statistics
PubMed Score 4.10
PubMed score by year
PubTator Score 3.77
PubTator score by year
Related Publications
Text Mined References (7)
GeneRif Annotations (1)
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PMID | Year | Title |
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