Tbio PCYT1B Choline-phosphate cytidylyltransferase B

Protein Summary

Description

Controls phosphatidylcholine synthesis. The protein encoded by this gene belongs to the cytidylyltransferase family. It is involved in the regulation of phosphatidylcholine biosynthesis. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Uniprot Accession IDs

• Q9Y5K3
• A8IX00
• B2RCX8
• B4DK10
• E9PD84
• O60621
• Q86XC9

Gene Name

• PCYT1B

Ensembl ID

• ENST00000356768
• ENSP00000349211
• ENSG00000102230
• ENST00000379144
• ENSP00000368439
• ENST00000379145
• ENSP00000368440

Symbol

• CCTB
• CTB
• CCTB

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.95
metabolite	0.78
gene perturbation	0.69
PubMedID	0.67
kinase	0.63

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.02   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 52   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.02   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 52   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0