Tbio UTP18 U3 small nucleolar RNA-associated protein 18 homolog

Protein Summary

Description

Involved in nucleolar processing of pre-18S ribosomal RNA.

Uniprot Accession IDs

• Q9Y5J1
• Q9H4N6

Gene Name

• UTP18

Ensembl ID

• ENST00000225298
• ENSP00000225298
• ENSG00000011260

Symbol

• WDR50
• WDR50
• CGI-48

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	0.98
cell type or tissue	0.96
drug perturbation	0.96
transcription factor binding site profile	0.9
histone modification site profile	0.89

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.38   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 61   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.38   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0