Tbio CSDC2 Cold shock domain-containing protein C2

Protein Summary

Description

RNA-binding factor which binds specifically to the very 3'-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity).

Uniprot Accession IDs

• Q9Y534
• Q8ND37

Gene Name

• CSDC2

Ensembl ID

• ENST00000306149
• ENSP00000302485
• ENSG00000172346

Symbol

• PIPPIN
• PIPPIN
• dJ347H13.2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.72
gene perturbation	0.66
protein domain	0.58
tissue sample	0.58
transcription factor	0.56

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Cold Shock Domain-containing Protein C2

DTO Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Cold Shock Domain-containing Protein C2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.86   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 137   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.86   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 137   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0