Tbio CRYBG1 Beta/gamma crystallin domain-containing protein 1

Protein Summary

Description

May function as suppressor of malignant melanoma. It may exert its effects through interactions with the cytoskeleton.

Uniprot Accession IDs

• Q9Y4K1
• B4DU04
• O00296
• Q5VWJ2

Gene Name

• CRYBG1

Ensembl ID

• ENST00000369066
• ENSP00000358062
• ENSG00000112297

Symbol

• AIM1
• ST4
• AIM1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0
biological term	0
cell line	0
cell type or tissue	0
cellular component	0

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.44   (req: < 5)

Gene RIFs: 10   (req: <= 3)

Antibodies: 22   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.44   (req: >= 5)

Gene RIFs: 10   (req: > 3)

Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0