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Tdark
CEP170B
Centrosomal protein of 170 kDa protein B

Protein Classes
Protein Summary
Description
Plays a role in microtubule organization.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000414716
  • ENSP00000404151
  • ENSG00000099814
  • ENST00000556508
  • ENSP00000451249

Symbol
  • FAM68C
  • KIAA0284
  • FAM68C
  • CEP170R
  • KIAA0284
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.77
cell line
0.68
transcription factor
0.67
tissue
0.63
small molecule perturbation
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.4   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 40   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.4   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 40   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (2)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (25)
1 – 10 of 25
CEP170
Tbio
Novelty: 0.05342931
p_int: 0.999996279
p_ni: 0.000002286
p_wrong: 0.000001435
Score: 0.57
Data Source: BioPlex,STRINGDB
KIF2B
Tbio
Novelty: 0.09958244
p_int: 0.999984513
p_ni: 0.000015292
p_wrong: 1.95e-7
Score: 0.689
Data Source: BioPlex,STRINGDB
DEFA5
Tbio
Novelty: 0.00863727
p_int: 0.999928311
p_ni: 0.000066615
p_wrong: 0.000005074
Data Source: BioPlex
CARM1
Tchem
Family: Epigenetic
Novelty: 0.00623937
p_int: 0.943227085
p_ni: 0.056772915
Score: 0.2
Data Source: BioPlex,STRINGDB
GGT5
Tbio
Family: Enzyme
Novelty: 0.00602505
Score: 0.711
Data Source: STRINGDB
C6orf201
Tdark
Novelty: 51
Score: 0.645
Data Source: STRINGDB
PAPSS1
Tbio
Family: Enzyme
Novelty: 0.01784751
Score: 0.59
Data Source: STRINGDB
DYNLL1
Tbio
Novelty: 0.00397334
Score: 0.558
Data Source: STRINGDB
ULK2
Tchem
Family: Kinase
Novelty: 0.02285321
Score: 0.531
Data Source: STRINGDB
CCDC73
Tdark
Novelty: 0.80048057
Score: 0.53
Data Source: STRINGDB
Publication Statistics
PubMed Score  3.40

PubMed score by year
PubTator Score  1.98

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer