Protein Summary
DNA helicase that modulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. Not able to remodel mononucleosomes in vitro (By similarity).
- ENST00000409535
- ENSP00000386520
- ENSG00000164080
- ARIP4
- KIAA0809
- ARIP4
- HSPC325
- SRISNF2L
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.98 | ||
small molecule perturbation | 0.64 | ||
cell line | 0.62 | ||
tissue sample | 0.59 | ||
protein domain | 0.58 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 4.89 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 130 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 4.89 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 130 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (27)
PIAS4
Family: TF
Novelty: 0.01388547
p_int: 0.999997739
p_ni: 0.000002244
p_wrong: 1.7e-8
Score: 0.196
Data Source: BioPlex,STRINGDB
DYRK1B
Family: Kinase
Novelty: 0.01960932
p_int: 0.999997502
p_ni: 0.000002496
p_wrong: 2e-9
Score: 0.193
Data Source: BioPlex,STRINGDB
DCAF7
Novelty: 0.02609518
p_int: 0.999971984
p_ni: 0.000027884
p_wrong: 1.32e-7
Score: 0.52
Data Source: BioPlex,STRINGDB
ADPRHL2
Family: Enzyme
Novelty: 0.02261777
p_int: 0.998325612
p_ni: 0.001674388
p_wrong: 1e-9
Data Source: BioPlex
DYRK1A
Family: Kinase
Novelty: 0.00226963
p_int: 0.997312181
p_ni: 0.002687796
p_wrong: 2.3e-8
Score: 0.607
Data Source: BioPlex,STRINGDB
PCDHAC2
Novelty: 0.28397695
p_int: 0.760256327
p_ni: 0.000076634
p_wrong: 0.239667039
Score: 0.218
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (1)
PathwayCommons (1)
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
PathwayCommons: netpath | AndrogenReceptor | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
AndrogenReceptor | ||||
Viral Interactions (0)
Gene Ontology Terms (4)
Functions (3)
Components (1)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations ()
GWAS Traits (5)
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
1 | 1 | 0 | 1.1 | 58.4 | |||||
mathematical ability | 1 | 1 | 1 | 46.1 | |||||
testosterone measurement | 1 | 1 | 1 | 42.3 | |||||
macrophage inflammatory protein 1b measurement | 1 | 2 | 2 | 40.4 | |||||
self reported educational attainment | 1 | 1 | 1 | 35 | |||||
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.1 | 58.4 | |||||
mathematical ability | 1 | 46.1 | |||||
testosterone measurement | 1 | 42.3 | |||||
macrophage inflammatory protein 1b measurement | 2 | 40.4 | |||||
self reported educational attainment | 1 | 35 | |||||
Find similar targets by:
IDG Resources
Orthologs (13)
1 – 5 of 13
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | RAD54 like 2 | 745605 | ||||||
Macaque | RAD54 like 2 [Source:HGNC Symbol;Acc:HGNC:29123] | |||||||
Mouse | MGI:1933196 | 81000 | ||||||
Rat | RGD:1561889 | 363135 | ||||||
Dog | RAD54 like 2 | VGNC:49612 | 476608 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | RAD54 like 2 | |||||
Macaque | RAD54 like 2 [Source:HGNC Symbol;Acc:HGNC:29123] | |||||
Mouse | ||||||
Rat | ||||||
Dog | RAD54 like 2 | |||||
Publication Statistics
PubMed Score 4.89
PubMed score by year
PubTator Score 4.15
PubTator score by year
Related Publications
Text Mined References (9)
GeneRif Annotations (3)
Items per page:
0 of 0
PMID | Year | Title |
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