Tbio PYGO1 Pygopus homolog 1

Protein Summary

Description

Involved in signal transduction through the Wnt pathway.

Uniprot Accession IDs

• Q9Y3Y4
• A7Y2D6

Gene Name

• PYGO1

Ensembl ID

• ENST00000302000
• ENSP00000302327
• ENSG00000171016
• ENST00000563719
• ENSP00000457777
• ENST00000645724
• ENSP00000496139

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.76
protein domain	0.73
cell type or tissue	0.55
biological process	0.54
histone modification site profile	0.46

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.28   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 153   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.28   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 153   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0