Protein Summary
This gene encodes a protein that co-purifies with human nucleoli. A similar protein in budding yeast is a component of pre-60S ribosomal particles, and is required for the early maturation steps of the 60S subunit. [provided by RefSeq, Jul 2008]
- ENST00000366932
- ENSP00000355899
- ENSG00000067533
- KIAA0507
- CGI-115
- KIAA0507
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.9 | ||
transcription factor binding site profile | 0.9 | ||
transcription factor perturbation | 0.88 | ||
microRNA | 0.84 | ||
kinase perturbation | 0.81 | ||
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.85 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 48 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.85 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 48 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Gene Ontology Terms (2)
Components (1)
Processes (1)
Items per page:
10
1 – 1 of 1
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Protein-Protein Interactions (237)
1 – 10 of 237
PPAN
Novelty: 0.0010549
p_int: 0.982660904
p_ni: 0.017339096
Score: 0.975
Data Source: BioPlex,STRINGDB
WDR46
Novelty: 0.36421448
p_int: 0.88293889
p_ni: 0.11706111
Score: 0.903
Data Source: BioPlex,STRINGDB
RPL11
Novelty: 0.00566877
p_int: 0.84651705
p_ni: 0.15348295
Score: 0.283
Data Source: BioPlex,STRINGDB
NIFK
Novelty: 0.02038052
Score: 0.996
Data Source: STRINGDB
SURF6
Novelty: 0.06528836
Score: 0.991
Data Source: STRINGDB
RPF2
Novelty: 0.08174387
Score: 0.991
Data Source: STRINGDB
RRS1
Novelty: 0.00929224
Score: 0.99
Data Source: STRINGDB
RBM28
Novelty: 0.01991731
Score: 0.987
Data Source: STRINGDB
WDR74
Novelty: 0.10605391
Score: 0.987
Data Source: STRINGDB
RPF1
Novelty: 8
Score: 0.985
Data Source: STRINGDB
Publication Statistics
PubMed Score 1.85
PubMed score by year
PubTator Score 1.05
PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
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