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Tdark
RRP15
RRP15-like protein

Protein Summary
Description
This gene encodes a protein that co-purifies with human nucleoli. A similar protein in budding yeast is a component of pre-60S ribosomal particles, and is required for the early maturation steps of the 60S subunit. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000366932
  • ENSP00000355899
  • ENSG00000067533

Symbol
  • KIAA0507
  • CGI-115
  • KIAA0507
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.9
transcription factor binding site profile
0.9
transcription factor perturbation
0.88
microRNA
0.84
kinase perturbation
0.81


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.85   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 48   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.85   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 48   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (237)
1 – 10 of 237
PPAN
Tbio
Novelty: 0.0010549
p_int: 0.982660904
p_ni: 0.017339096
Score: 0.975
Data Source: BioPlex,STRINGDB
WDR46
Tdark
Novelty: 0.36421448
p_int: 0.88293889
p_ni: 0.11706111
Score: 0.903
Data Source: BioPlex,STRINGDB
RPL11
Tbio
Novelty: 0.00566877
p_int: 0.84651705
p_ni: 0.15348295
Score: 0.283
Data Source: BioPlex,STRINGDB
NIFK
Tbio
Novelty: 0.02038052
Score: 0.996
Data Source: STRINGDB
SURF6
Tbio
Novelty: 0.06528836
Score: 0.991
Data Source: STRINGDB
RPF2
Tbio
Novelty: 0.08174387
Score: 0.991
Data Source: STRINGDB
RRS1
Tbio
Novelty: 0.00929224
Score: 0.99
Data Source: STRINGDB
RBM28
Tbio
Novelty: 0.01991731
Score: 0.987
Data Source: STRINGDB
WDR74
Tbio
Novelty: 0.10605391
Score: 0.987
Data Source: STRINGDB
RPF1
Tdark
Novelty: 8
Score: 0.985
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.85

PubMed score by year
PubTator Score  1.05

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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