Tbio MRPL11 39S ribosomal protein L11, mitochondrial

Protein Summary

Description

This nuclear gene encodes a 39S subunit component of the mitochondial ribosome. Alternative splicing results in multiple transcript variants. Pseudogenes for this gene are found on chromosomes 5 and 12. [provided by RefSeq, May 2014]

Uniprot Accession IDs

• Q9Y3B7
• A6NLT0
• A8K219
• Q32P46
• Q96Q73
• L11mt

Gene Name

• MRPL11

Ensembl ID

• ENST00000310999
• ENSP00000308897
• ENSG00000174547
• ENST00000329819
• ENSP00000329630
• ENST00000430466
• ENSP00000415356

Symbol

• L11MT
• CGI-113
• MRP-L11

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.96
virus perturbation	0.96
histone modification site profile	0.91
disease perturbation	0.87
transcription factor binding site profile	0.84

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Ribosomal Protein / 39s Ribosomal Protein L11, Mitochondrial

DTO Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Ribosomal Protein / 39s Ribosomal Protein L11, Mitochondrial

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.57   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 273   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.57   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 273   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0