SF3B6
Splicing factor 3B subunit 6
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.9 | ||
small molecule perturbation | 0.81 | ||
histone modification site profile | 0.77 | ||
transcription factor | 0.7 | ||
transcription factor binding site profile | 0.7 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism of RNA | ||||
Reactome | Processing of Capped Intron-Containing Pre-mRNA | ||||
Reactome | mRNA Splicing | ||||
Reactome | mRNA Splicing - Major Pathway | ||||
Reactome | mRNA Splicing - Minor Pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism of RNA | ||||
Processing of Capped Intron-Containing Pre-mRNA | ||||
mRNA Splicing | ||||
mRNA Splicing - Major Pathway | ||||
mRNA Splicing - Minor Pathway | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
reticulocyte measurement | 3 | 5 | 8 | 98.6 | |||||
reticulocyte count | 7 | 4 | 13 | 97.4 | |||||
lymphocyte count | 2 | 3 | 3 | 96.6 | |||||
mean corpuscular volume | 1 | 3 | 3 | 94.9 | |||||
lymphocyte percentage of leukocytes | 2 | 3 | 3 | 86.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
reticulocyte measurement | 8 | 98.6 | |||||
reticulocyte count | 13 | 97.4 | |||||
lymphocyte count | 3 | 96.6 | |||||
mean corpuscular volume | 3 | 94.9 | |||||
lymphocyte percentage of leukocytes | 3 | 86.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | splicing factor 3b subunit 6 | VGNC:6398 | 459061 | |||||
Macaque | splicing factor 3b subunit 6 | 704090 | ||||||
Mouse | MGI:1913305 | 66055 | ||||||
Dog | splicing factor 3b subunit 6 | VGNC:46074 | 475682 | |||||
Horse | splicing factor 3b subunit 6 | VGNC:22893 | 100056247 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | splicing factor 3b subunit 6 | |||||
Macaque | splicing factor 3b subunit 6 | |||||
Mouse | ||||||
Dog | splicing factor 3b subunit 6 | |||||
Horse | splicing factor 3b subunit 6 | |||||
PMID | Year | Title |
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