You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
PLLP
Plasmolipin

Protein Summary
Description
Appears to be involved in myelination. Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent and K(+)-selective (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000219207
  • ENSP00000219207
  • ENSG00000102934

Symbol
  • PMLP
  • TM4SF11
  • PMLP
  • TM4SF11
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.9
histone modification site profile
0.74
PubMedID
0.74
transcription factor binding site profile
0.66
transcription factor perturbation
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 44.77   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 90   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 44.77   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 90   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
2
2
2
65.1
mean corpuscular hemoglobin concentration
2
2
2
57.5
hemoglobin measurement
2
2
2
52.8
high density lipoprotein cholesterol measurement
1
1
1
52.8
red blood cell density measurement
1
1
1
9.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
2
65.1
mean corpuscular hemoglobin concentration
2
57.5
hemoglobin measurement
2
52.8
high density lipoprotein cholesterol measurement
1
52.8
red blood cell density measurement
1
9.3
Gene Ontology Terms (7)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (47)
1 – 10 of 47
MYADM
Tbio
Novelty: 0.11475375
Score: 0.902
Data Source: STRINGDB
PLP1
Tbio
Novelty: 0.00129083
Score: 0.735
Data Source: STRINGDB
CKLF
Tbio
Novelty: 0.01452927
Score: 0.718
Data Source: STRINGDB
MAL
Tbio
Novelty: 0.03081736
Score: 0.696
Data Source: STRINGDB
SLC5A3
Tbio
Family: Transporter
Novelty: 0.01687313
Score: 0.669
Data Source: STRINGDB
CNP
Tbio
Family: Enzyme
Novelty: 0.00566142
Score: 0.651
Data Source: STRINGDB
STX1B
Tbio
Novelty: 0.01171833
Score: 0.627
Data Source: STRINGDB
PMP22
Tbio
Novelty: 0.00256307
Score: 0.595
Data Source: STRINGDB
BCAS1
Tbio
Novelty: 0.06076252
Score: 0.559
Data Source: STRINGDB
GFAP
Tbio
Novelty: 0.00020932
Score: 0.548
Data Source: STRINGDB
Publication Statistics
PubMed Score  44.77

PubMed score by year
PubTator Score  9.45

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer