MAP3K2
Mitogen-activated protein kinase kinase kinase 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
drug perturbation | 1 | ||
molecular function | 0.99 | ||
hub protein | 0.92 | ||
virus perturbation | 0.9 | ||
small molecule perturbation | 0.81 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
KEGG | GnRH signaling pathway | ||||
KEGG | Gap junction | ||||
KEGG | MAPK signaling pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
GnRH signaling pathway | ||||
Gap junction | ||||
MAPK signaling pathway | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
protein C measurement | 3 | 5 | 6 | 96.7 | |||||
self reported educational attainment | 1 | 1 | 1 | 4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
protein C measurement | 6 | 96.7 | |||||
self reported educational attainment | 1 | 4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | mitogen-activated protein kinase kinase kinase 2 | VGNC:14152 | 736244 | |||||
Macaque | mitogen-activated protein kinase kinase kinase 2 | 100424131 | ||||||
Mouse | MGI:1346873 | 26405 | ||||||
Rat | RGD:620967 | 171492 | ||||||
Dog | mitogen-activated protein kinase kinase kinase 2 | VGNC:42972 | 612902 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | mitogen-activated protein kinase kinase kinase 2 | |||||
Macaque | mitogen-activated protein kinase kinase kinase 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | mitogen-activated protein kinase kinase kinase 2 | |||||
PMID | Year | Title |
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