Tbio ZKSCAN5 Zinc finger protein with KRAB and SCAN domains 5

Protein Summary

Description

May be involved in transcriptional regulation. This gene encodes a zinc finger protein of the Kruppel family. The protein contains a SCAN box and a KRAB A domain and may be involved in transcriptional regulation. A similar protein in mouse is differentially expressed in spermatogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Uniprot Accession IDs

• Q9Y2L8
• A4D280
• D6W5S9

Gene Name

• ZKSCAN5

Ensembl ID

• ENST00000326775
• ENSP00000322872
• ENSG00000196652
• ENST00000394170
• ENSP00000377725
• ENST00000451158
• ENSP00000392104

Symbol

• KIAA1015
• ZFP95
• ZFP95
• ZFP-95
• ZNF914
• ZSCAN37

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	0.97
protein domain	0.85
transcription factor binding site profile	0.78
transcription factor	0.72
virus perturbation	0.64

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.66   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 105   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.66   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 105   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0