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Tbio
EPB41L3
Band 4.1-like protein 3

Protein Summary
Description
Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N-methyltransferases, including PRMT3 and PRMT5.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000341928
  • ENSP00000343158
  • ENSG00000082397
  • ENST00000540638
  • ENSP00000442091
  • ENST00000544123
  • ENSP00000441174

Symbol
  • DAL1
  • KIAA0987
  • 4.1B
  • DAL1
  • DAL-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
1
transcription factor perturbation
0.98
hub protein
0.95
interacting protein
0.95
gene perturbation
0.84


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 102.18   (req: < 5)
Gene RIFs: 55   (req: <= 3)
Antibodies: 228   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 102.18   (req: >= 5)
Gene RIFs: 55   (req: > 3)
Antibodies: 228   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 15
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0