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Tbio
WDR37
WD repeat-containing protein 37

Protein Summary
Description
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000263150
  • ENSP00000263150
  • ENSG00000047056
  • ENST00000358220
  • ENSP00000350954

Symbol
  • KIAA0982
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.9
kinase perturbation
0.88
virus perturbation
0.85
histone modification site profile
0.79
disease perturbation
0.74


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.98   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 139   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.98   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 139   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
creatinine measurement
1
1
1
16.9
glomerular filtration rate
1
1
1
16.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
creatinine measurement
1
16.9
glomerular filtration rate
1
16.9
Gene Ontology Terms (2)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (120)
1 – 10 of 120
PACS1
Tbio
Novelty: 0.02030091
p_int: 0.999999966
p_ni: 2.1e-8
p_wrong: 1.2e-8
Score: 0.888
Data Source: BioPlex,STRINGDB
LRRC46
Tdark
Novelty: 1.159245
p_int: 0.999999615
p_ni: 3.84e-7
Score: 0.223
Data Source: BioPlex,STRINGDB
PACS2
Tbio
Novelty: 0.00887813
p_int: 0.999999484
p_ni: 3.75e-7
p_wrong: 1.41e-7
Score: 0.904
Data Source: BioPlex,STRINGDB
LEAP2
Tbio
Novelty: 0.01484908
p_int: 0.999996364
p_ni: 0.000003636
Data Source: BioPlex
SGF29
Tbio
Family: Epigenetic
Novelty: 0.0426456
p_int: 0.997771968
p_ni: 0.000941501
p_wrong: 0.001286531
Score: 0.327
Data Source: BioPlex,STRINGDB
RBM14
Tbio
Novelty: 0.01286049
p_int: 0.996987423
p_ni: 0.000715689
p_wrong: 0.002296889
Data Source: BioPlex
CLUH
Tbio
Novelty: 0.14027296
p_int: 0.996747686
p_ni: 0.003252314
Score: 0.185
Data Source: BioPlex,STRINGDB
IQCF1
Tdark
Novelty: 0.78525464
p_int: 0.996398104
p_ni: 0.002859808
p_wrong: 0.000742088
Data Source: BioPlex
CAPN2
Tchem
Novelty: 0.00431673
p_int: 0.964450134
p_ni: 0.031907804
p_wrong: 0.003642062
Data Source: BioPlex
SETD2
Tchem
Family: Epigenetic
Novelty: 0.00178899
p_int: 0.922332707
p_ni: 0.077667159
p_wrong: 1.34e-7
Score: 0.274
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  5.98

PubMed score by year
PubTator Score  0.38

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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