Tchem STK38L Serine/threonine-protein kinase 38-like

Protein Summary

Description

Involved in the regulation of structural processes in differentiating and mature neuronal cells.

Uniprot Accession IDs

• Q9Y2H1
• A8K4U0
• B4E3J8
• Q8TBX7

Gene Name

• STK38L

Ensembl ID

• ENST00000389032
• ENSP00000373684
• ENSG00000211455

Symbol

• KIAA0965
• NDR2
• NDR2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.96
protein domain	0.92
transcription factor binding site profile	0.88
kinase perturbation	0.84
transcription factor perturbation	0.84

Protein Classes

PANTHER Classes

Protein / Transferase / Kinase / Protein Kinase / Non-receptor Serine/threonine Protein Kinase / Serine/threonine-protein Kinase 38-like

Protein / Transfer/carrier Protein / Serine/threonine-protein Kinase 38-like

Protein / Calcium-binding Protein / Intracellular Calcium-sensing Protein / Calmodulin / Serine/threonine-protein Kinase 38-like

Protein / Calcium-binding Protein / Annexin / Serine/threonine-protein Kinase 38-like

DTO Classes

Protein / Kinase / Protein Kinase / Agc Group / Ndr Family / Serine/threonine-protein Kinase 38-like

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28.09   (req: < 5)

Gene RIFs: 18   (req: <= 3)

Antibodies: 223   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28.09   (req: >= 5)

Gene RIFs: 18   (req: > 3)

Antibodies: 223   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0