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Tdark
DNAJC16
DnaJ homolog subfamily C member 16

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.24   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 30   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.24   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 30   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
5
5
4
8.2
90.6
creatinine measurement
2
2
2
51.3
chronotype measurement
1
1
1
48.4
hematocrit
1
1
1
7.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
4
8.2
90.6
creatinine measurement
2
51.3
chronotype measurement
1
48.4
hematocrit
1
7.3
Gene Ontology Terms (3)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
GOC
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (84)
1 – 10 of 84
BTNL8
Tdark
Novelty: 0.40339869
p_int: 0.978647484
p_ni: 0.021352516
Score: 0.205
Data Source: BioPlex,STRINGDB
SEC23IP
Tbio
Novelty: 0.0925721
p_int: 0.956059335
p_ni: 0.043940664
p_wrong: 1e-9
Data Source: BioPlex
ECEL1
Tbio
Family: Enzyme
Novelty: 0.01488521
p_int: 0.923131056
p_ni: 0.076868835
p_wrong: 1.09e-7
Data Source: BioPlex
CLEC4A
Tbio
Novelty: 0.01821643
p_int: 0.912533195
p_ni: 0.087466805
Data Source: BioPlex
ITM2A
Tbio
Novelty: 0.06374858
p_int: 0.900596601
p_ni: 0.099403399
Score: 0.193
Data Source: BioPlex,STRINGDB
NKAIN1
Tdark
Family: Enzyme
Novelty: 0.52190272
p_int: 0.835930529
p_ni: 0.164069471
Data Source: BioPlex
CLEC2B
Tbio
Novelty: 0.06581244
p_int: 0.804882241
p_ni: 0.195117759
Data Source: BioPlex
SCNN1D
Tbio
Family: IC
Novelty: 0.06191685
p_int: 0.754996087
p_ni: 0.245003913
Score: 0.235
Data Source: BioPlex,STRINGDB
CEP85
Tdark
Novelty: 0.2789146
Score: 0.656
Data Source: STRINGDB
CLPB
Tbio
Family: Enzyme
Novelty: 0.00209789
Score: 0.642
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.24

PubMed score by year
PubTator Score  0.5

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer