BTRC
F-box/WD repeat-containing protein 1A
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 1 | ||
disease perturbation | 0.99 | ||
biological process | 0.97 | ||
hub protein | 0.92 | ||
protein domain | 0.92 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | APC/C-mediated degradation of cell cycle proteins | ||||
Reactome | Activation of NF-kappaB in B cells | ||||
Reactome | Adaptive Immune System | ||||
Reactome | Antigen processing: Ubiquitination & Proteasome degradation | ||||
Reactome | C-type lectin receptors (CLRs) | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
APC/C-mediated degradation of cell cycle proteins | ||||
Activation of NF-kappaB in B cells | ||||
Adaptive Immune System | ||||
Antigen processing: Ubiquitination & Proteasome degradation | ||||
C-type lectin receptors (CLRs) | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Experiment (EXP) | Reactome | |||
Inferred from Direct Assay (IDA) | ParkinsonsUK-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
red blood cell distribution width | 1 | 1 | 1 | 64.9 | |||||
smoking status measurement | 2 | 2 | 2 | 55.8 | |||||
diastolic blood pressure | 1 | 1 | 1 | 40.7 | |||||
gait measurement | 1 | 1 | 1 | 39.6 | |||||
erythrocyte count | 1 | 1 | 1 | 17.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
red blood cell distribution width | 1 | 64.9 | |||||
smoking status measurement | 2 | 55.8 | |||||
diastolic blood pressure | 1 | 40.7 | |||||
gait measurement | 1 | 39.6 | |||||
erythrocyte count | 1 | 17.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | beta-transducin repeat containing E3 ubiquitin protein ligase | 711843 | ||||||
Mouse | MGI:1338871 | 12234 | ||||||
Rat | RGD:1359721 | 361765 | ||||||
Dog | beta-transducin repeat containing E3 ubiquitin protein ligase | VGNC:38564 | 486851 | |||||
Horse | beta-transducin repeat containing E3 ubiquitin protein ligase | VGNC:15923 | 100070200 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | beta-transducin repeat containing E3 ubiquitin protein ligase | |||||
Mouse | ||||||
Rat | ||||||
Dog | beta-transducin repeat containing E3 ubiquitin protein ligase | |||||
Horse | beta-transducin repeat containing E3 ubiquitin protein ligase | |||||
PMID | Year | Title |
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