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Tbio
ERGIC3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

Protein Summary
Description
Possible role in transport between endoplasmic reticulum and Golgi.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000348547
  • ENSP00000341358
  • ENSG00000125991
  • ENST00000357394
  • ENSP00000349970

Symbol
  • C20orf47
  • ERV46
  • SDBCAG84
  • Erv46
  • CGI-54
  • C2orf47
  • PRO0989
  • C20orf47
  • NY-BR-84
  • SDBCAG84
  • dJ477O4.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
1
histone modification site profile
0.92
interacting protein
0.91
kinase perturbation
0.76
cellular component
0.55


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.01   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 232   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.01   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 232   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
2
2
3
88.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
3
88.6
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ERGIC and golgi 3
VGNC:10153
458205
Macaque
ERGIC and golgi 3
704736
Mouse
MGI:1913616
66366
Rat
RGD:1308144
296306
Dog
ERGIC and golgi 3
VGNC:40452
477212
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ERGIC and golgi 3
Macaque
ERGIC and golgi 3
Mouse
Rat
Dog
ERGIC and golgi 3
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9Y282-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (8)
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (96)
1 – 10 of 96
ERGIC2
Tbio
Novelty: 0.08610944
p_int: 0.999997184
p_ni: 0.000002816
Score: 0.902
Data Source: BioPlex,STRINGDB
ANKRD13D
Tdark
Novelty: 2.14380936
p_int: 0.999811491
p_ni: 0.000188509
Data Source: BioPlex
YIPF3
Tbio
Novelty: 0.12021667
p_int: 0.998333241
p_ni: 0.001666759
Score: 0.286
Data Source: BioPlex,STRINGDB
DOLK
Tbio
Family: Enzyme
Novelty: 0.00664639
p_int: 0.995591599
p_ni: 0.004345223
p_wrong: 0.000063178
Score: 0.154
Data Source: BioPlex,STRINGDB
SLC16A13
Tbio
Family: Transporter
Novelty: 0.15843384
p_int: 0.9929235
p_ni: 0.001718654
p_wrong: 0.005357846
Score: 0.222
Data Source: BioPlex,STRINGDB
CLPTM1
Tbio
Novelty: 0.06426049
p_int: 0.992808716
p_ni: 0.007191284
Score: 0.224
Data Source: BioPlex,STRINGDB
TMEM87A
Tdark
Novelty: 0.33614983
p_int: 0.991157573
p_ni: 0.008842425
p_wrong: 2e-9
Score: 0.183
Data Source: BioPlex,STRINGDB
EXT1
Tbio
Family: Enzyme
Novelty: 0.00355951
p_int: 0.990752855
p_ni: 0.009247145
Score: 0.22
Data Source: BioPlex,STRINGDB
COPG1
Tbio
Novelty: 0.01331193
p_int: 0.982275488
p_ni: 0.017724512
Score: 0.364
Data Source: BioPlex,STRINGDB
ZFPL1
Tbio
Novelty: 0.1829181
p_int: 0.981998378
p_ni: 0.018001622
p_wrong: 1e-9
Data Source: BioPlex
Publication Statistics
PubMed Score  12.01

PubMed score by year
PubTator Score  5

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer