You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
RNF24
RING finger protein 24

Protein Summary
Description
May play a role in TRPCs intracellular trafficking. This gene encodes an integral membrane protein that contains a RING-type zinc finger. The encoded protein may interact with multiple transient receptor potential cation channel subfamily C (TRPC) proteins and regulate the trafficking and insertion of these proteins into the plasma membrane. [provided by RefSeq, Mar 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000336095
  • ENSP00000336753
  • ENSG00000101236
  • ENST00000358395
  • ENSP00000351166
  • ENST00000432261
  • ENSP00000388550
  • ENST00000545616
  • ENSP00000444711

Symbol
  • G1L
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
0.79
transcription factor binding site profile
0.78
transcription factor
0.71
kinase perturbation
0.66
tissue sample
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.39   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 107   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.39   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 107   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0