Tbio NIP7 60S ribosome subunit biogenesis protein NIP7 homolog

Protein Summary

Description

Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.

Uniprot Accession IDs

• Q9Y221
• B2RD04
• Q9NZZ0

Gene Name

• NIP7

Ensembl ID

• ENST00000254940
• ENSP00000254940
• ENSG00000132603
• ENST00000254941
• ENSP00000254941

Symbol

• KD93
• CGI-37
• HSPC031

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.98
transcription factor perturbation	0.91
disease perturbation	0.83
transcription factor binding site profile	0.82
interacting protein	0.81

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.24   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 213   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.24   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 213   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0