SMC3
Structural maintenance of chromosomes protein 3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
interacting protein | 1 | ||
hub protein | 0.99 | ||
molecular function | 0.98 | ||
protein complex | 0.98 | ||
transcription factor binding site profile | 0.92 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cell Cycle | ||||
Reactome | Cell Cycle, Mitotic | ||||
Reactome | Cohesin Loading onto Chromatin | ||||
Reactome | ESR-mediated signaling | ||||
Reactome | Establishment of Sister Chromatid Cohesion | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cell Cycle | ||||
Cell Cycle, Mitotic | ||||
Cohesin Loading onto Chromatin | ||||
ESR-mediated signaling | ||||
Establishment of Sister Chromatid Cohesion | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 2 | 1 | 2 | 71.9 | |||||
electrocardiography | 1 | 1 | 3 | 47.7 | |||||
serum non-albumin protein measurement | 1 | 1 | 1 | 24.5 | |||||
bone density | 1 | 1 | 1 | 17.8 | |||||
acute respiratory distress syndrome | 1 | 1 | 0 | 1.7 | 0.4 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 2 | 71.9 | |||||
electrocardiography | 3 | 47.7 | |||||
serum non-albumin protein measurement | 1 | 24.5 | |||||
bone density | 1 | 17.8 | |||||
acute respiratory distress syndrome | 0 | 1.7 | 0.4 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | structural maintenance of chromosomes 3 | VGNC:5786 | 450731 | |||||
Macaque | structural maintenance of chromosomes 3 | 695123 | ||||||
Mouse | MGI:1339795 | 13006 | ||||||
Rat | RGD:62006 | 29486 | ||||||
Dog | structural maintenance of chromosomes 3 | VGNC:46544 | 486886 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | structural maintenance of chromosomes 3 | |||||
Macaque | structural maintenance of chromosomes 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | structural maintenance of chromosomes 3 | |||||
PMID | Year | Title |
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