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Tbio
IQSEC3
IQ motif and SEC7 domain-containing protein 3

Protein Summary
Description
Acts as a guanine nucleotide exchange factor (GEF) for ARF1.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000382841
  • ENSP00000372292
  • ENSG00000120645
  • ENST00000538872
  • ENSP00000437554
  • ENST00000571363
  • ENSP00000461043
  • ENSG00000262607

Symbol
  • KIAA1110
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.73
phenotype
0.64
trait
0.61
cell line
0.59
tissue sample
0.57


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.43   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 60   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.43   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 60   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0