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Tbio
SCAF8
Protein SCAF8

Protein Summary
Description
May play a role in mRNA processing.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000367178
  • ENSP00000356146
  • ENSG00000213079
  • ENST00000367186
  • ENSP00000356154

Symbol
  • CCAP7
  • KIAA1116
  • RBM16
  • RBM16
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.88
histone modification site profile
0.81
transcription factor binding site profile
0.74
interacting protein
0.73
protein domain
0.73


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.32   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 83   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.32   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 83   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
daytime rest measurement
1
1
1
52.4
1
1
0
1
31.4
glomerular filtration rate
2
1
2
12.9
creatinine measurement
1
1
1
9.4
serum urea measurement
1
1
1
3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
daytime rest measurement
1
52.4
0
1
31.4
glomerular filtration rate
2
12.9
creatinine measurement
1
9.4
serum urea measurement
1
3
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
SR-related CTD associated factor 8
VGNC:9523
472167
Macaque
SR-related CTD associated factor 8
106998074
Mouse
MGI:1925212
106583
Rat
RGD:708362
245926
Dog
SR-related CTD associated factor 8
VGNC:53973
102153271
Species
Name
OMA
EggNOG
Inparanoid
Chimp
SR-related CTD associated factor 8
Macaque
SR-related CTD associated factor 8
Mouse
Rat
Dog
SR-related CTD associated factor 8
Protein Structure (9 Structures, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q9UPN6-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 5 of 9
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Gene Ontology Terms (11)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Physical Interaction (IPI)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (103)
1 – 10 of 103
NAGK
Tbio
Family:  Kinase
Novelty:  0.01603908
p_int:  0.999988614
p_ni:  0.000011386
Score:  0.181
Data Source:  BioPlex,STRINGDB
KLHL22
Tbio
Novelty:  0.24456252
p_int:  0.999926768
p_ni:  0.000073232
Data Source:  BioPlex
CALML3
Tbio
Novelty:  0.0336689
p_int:  0.999423666
p_ni:  0.000576334
Data Source:  BioPlex
MINDY3
Tbio
Novelty:  0.02865765
p_int:  0.99941855
p_ni:  0.000581446
p_wrong:  4e-9
Score:  0.27
Data Source:  BioPlex,STRINGDB
JMJD6
Tchem
Family:  Enzyme
Novelty:  0.00305479
p_int:  0.996307177
p_ni:  0.00369282
p_wrong:  3e-9
Data Source:  BioPlex
DNPEP
Tchem
Family:  Enzyme
Novelty:  0.02415651
p_int:  0.993048658
p_ni:  0.00694506
p_wrong:  0.000006282
Score:  0.199
Data Source:  BioPlex,STRINGDB
MTUS2
Tbio
Novelty:  0.13504593
p_int:  0.931973817
p_ni:  0.065120653
p_wrong:  0.00290553
Score:  0.175
Data Source:  BioPlex,STRINGDB
THRSP
Tbio
Novelty:  0.00938864
p_int:  0.913362071
p_ni:  0.086523072
p_wrong:  0.000114858
Data Source:  BioPlex
PCF11
Tbio
Novelty:  0.01882626
Score:  0.883
Data Source:  STRINGDB
SETX
Tbio
Family:  Enzyme
Novelty:  0.00474094
Score:  0.829
Data Source:  STRINGDB
Publication Statistics
PubMed Score  5.32

PubMed score by year
PubTator Score  3.17

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer