You are using an outdated browser. Please upgrade your browser to improve your experience.

Tchem
GPR34
Probable G-protein coupled receptor 34

Protein Summary
Description
Orphan receptor. G protein-coupled receptors (GPCRs), such as GPR34, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.[supplied by OMIM, Apr 2006]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000378138
  • ENSP00000367378
  • ENSG00000171659
  • ENST00000378142
  • ENSP00000367384
  • ENST00000649219
  • ENSP00000498130

Symbol
  • LYPSR1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.67
tissue sample
0.56
cell type or tissue
0.54
pathway
0.52
phenotype
0.47


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.7   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 275   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.7   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 275   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 6
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Protein-Protein Interactions (28)
EFHC2
Tbio
Novelty:  0.08795794
Score:  0.805
Data Source:  STRINGDB
TMEM119
Tbio
Novelty:  0.02762151
Score:  0.71
Data Source:  STRINGDB
C1QA
Tbio
Novelty:  0.00987917
Score:  0.683
Data Source:  STRINGDB
C1QC
Tbio
Novelty:  0.0286777
Score:  0.63
Data Source:  STRINGDB
TYROBP
Tbio
Family:  Enzyme
Novelty:  0.00410031
Score:  0.61
Data Source:  STRINGDB
TMIGD3
Tchem
Novelty:  0.00089511
Score:  0.574
Data Source:  STRINGDB
ADORA3
Tchem
Family:  GPCR
Novelty:  0.00089511
Score:  0.574
Data Source:  STRINGDB
CRYZL1
Tbio
Family:  Enzyme
Novelty:  0.04435286
Score:  0.573
Data Source:  STRINGDB
GPR3
Tchem
Family:  GPCR
Novelty:  0.02331106
Score:  0.57
Data Source:  STRINGDB
OLFML3
Tbio
Novelty:  0.09742366
Score:  0.555
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
Find similar targets by:
IDG Resources
Genetic Construct
GPR34-Tango
image for GPR34-Tango
Details:
  • Vector:  addgene66353
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  FLAG
Data:
  • GPR34-Tango
Order Genetic Construct from:
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
G protein-coupled receptor 34
VGNC:1377
473572
Macaque
G protein-coupled receptor 34
700887
Mouse
MGI:1346334
23890
Rat
RGD:1563681
554353
Dog
G protein-coupled receptor 34
VGNC:41431
100683845
Species
Name
OMA
EggNOG
Inparanoid
Chimp
G protein-coupled receptor 34
Macaque
G protein-coupled receptor 34
Mouse
Rat
Dog
G protein-coupled receptor 34
Publication Statistics
PubMed Score 31.70
PubMed score by year
PubTator Score 17.39
PubTator score by year
Patents
Patents by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title