Tbio WDR3 WD repeat-containing protein 3

Protein Summary

Description

This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q9UNX4

Gene Name

• WDR3

Ensembl ID

• ENST00000349139
• ENSP00000308179
• ENSG00000065183

Symbol

• DIP2
• UTP12

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.93
protein domain	0.85
kinase perturbation	0.81
cellular component	0.64
cell line	0.63

Protein Classes

DTO Classes

Wd Repeat-containing Protein 34

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.84   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 89   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.84   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 89   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0