ABCG2
ATP-binding cassette sub-family G member 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
chemical | 1 | ||
drug | 1 | ||
molecular function | 1 | ||
disease | 0.9 | ||
histone modification site profile | 0.86 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Abacavir transmembrane transport | ||||
Reactome | Abacavir transport and metabolism | ||||
Reactome | Iron uptake and transport | ||||
Reactome | Metabolism | ||||
Reactome | Transport of small molecules | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Abacavir transmembrane transport | ||||
Abacavir transport and metabolism | ||||
Iron uptake and transport | ||||
Metabolism | ||||
Transport of small molecules | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | ProtInc | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
urate measurement | 13 | 19 | 29 | 6 | 99.9 | ||||
uric acid measurement | 13 | 8 | 18 | 1.9 | 99.4 | ||||
15 | 8 | 0 | 1.9 | 99.2 | |||||
amino acid measurement | 4 | 4 | 5 | 94.1 | |||||
blood metabolite measurement | 2 | 4 | 6 | 94.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
urate measurement | 29 | 6 | 99.9 | ||||
uric acid measurement | 18 | 1.9 | 99.4 | ||||
0 | 1.9 | 99.2 | |||||
amino acid measurement | 5 | 94.1 | |||||
blood metabolite measurement | 6 | 94.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | ATP binding cassette subfamily G member 2 | VGNC:2951 | 471251 | |||||
Macaque | ATP binding cassette subfamily G member 2 (Junior blood group) | 574307 | ||||||
Mouse | MGI:1347061 | 26357 | ||||||
Rat | RGD:631345 | 312382 | ||||||
Dog | ATP binding cassette subfamily G member 2 | VGNC:49113 | 478472 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | ATP binding cassette subfamily G member 2 | |||||
Macaque | ATP binding cassette subfamily G member 2 (Junior blood group) | |||||
Mouse | ||||||
Rat | ||||||
Dog | ATP binding cassette subfamily G member 2 | |||||
PMID | Year | Title |
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