Tbio G3BP2 Ras GTPase-activating protein-binding protein 2

Protein Summary

Description

Probable scaffold protein that may be involved in mRNA transport.

Uniprot Accession IDs

• Q9UN86
• A8K6X1
• O60606
• O75149
• Q9UPA1
• G3BP-2

Gene Name

• G3BP2

Ensembl ID

• ENST00000357854
• ENSP00000350518
• ENSG00000138757
• ENST00000359707
• ENSP00000352738
• ENST00000395719
• ENSP00000379069

Symbol

• KIAA0660

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	1
transcription factor perturbation	0.98
ligand (protein) perturbation	0.96
disease perturbation	0.95
co-expressed gene	0.94

Protein Classes

PANTHER Classes

Protein / Signaling Molecule / Ras Gtpase-activating Protein-binding Protein 2

Protein / Nucleic Acid Binding / Rna Binding Protein / Ras Gtpase-activating Protein-binding Protein 2

DTO Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Ras Gtpase-activating Protein-binding Protein 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.13   (req: < 5)

Gene RIFs: 25   (req: <= 3)

Antibodies: 143   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.13   (req: >= 5)

Gene RIFs: 25   (req: > 3)

Antibodies: 143   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0