MYO6
Unconventional myosin-VI
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 1 | ||
molecular function | 0.99 | ||
interacting protein | 0.98 | ||
biological process | 0.87 | ||
microRNA | 0.84 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Gap junction degradation | ||||
Reactome | Gap junction trafficking | ||||
Reactome | Gap junction trafficking and regulation | ||||
Reactome | Glutamate binding, activation of AMPA receptors and synaptic plasticity | ||||
Reactome | Membrane Trafficking | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Gap junction degradation | ||||
Gap junction trafficking | ||||
Gap junction trafficking and regulation | ||||
Glutamate binding, activation of AMPA receptors and synaptic plasticity | ||||
Membrane Trafficking | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Traceable Author Statement (TAS) | UniProtKB | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 2 | 5 | 5 | 63.6 | |||||
1 | 1 | 0 | 1.1 | 15.8 | |||||
intelligence | 1 | 1 | 0 | 5.5 | 15.8 | ||||
BMI-adjusted waist circumference | 1 | 1 | 1 | 5.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 5 | 63.6 | |||||
0 | 1.1 | 15.8 | |||||
intelligence | 0 | 5.5 | 15.8 | ||||
BMI-adjusted waist circumference | 1 | 5.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | myosin VI | VGNC:11129 | 462831 | |||||
Macaque | myosin VI | 716634 | ||||||
Mouse | MGI:104785 | 17920 | ||||||
Rat | RGD:1560646 | 315840 | ||||||
Dog | myosin VI | VGNC:43571 | 481884 | |||||
PMID | Year | Title |
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