ZNRF3
E3 ubiquitin-protein ligase ZNRF3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.76 | ||
histone modification site profile | 0.74 | ||
transcription factor | 0.71 | ||
tissue sample | 0.63 | ||
cell line | 0.62 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Regulation of FZD by ubiquitination | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by WNT | ||||
Reactome | TCF dependent signaling in response to WNT | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Regulation of FZD by ubiquitination | ||||
Signal Transduction | ||||
Signaling by WNT | ||||
TCF dependent signaling in response to WNT | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 3 | 14 | 19 | 99.5 | |||||
cup-to-disc ratio measurement | 4 | 5 | 6 | 97.7 | |||||
BMI-adjusted waist-hip ratio | 10 | 5 | 20 | 96.7 | |||||
waist-hip ratio | 7 | 6 | 11 | 95.2 | |||||
red blood cell distribution width | 4 | 3 | 4 | 93.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 19 | 99.5 | |||||
cup-to-disc ratio measurement | 6 | 97.7 | |||||
BMI-adjusted waist-hip ratio | 20 | 96.7 | |||||
waist-hip ratio | 11 | 95.2 | |||||
red blood cell distribution width | 4 | 93.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | zinc and ring finger 3 | VGNC:7810 | 458737 | |||||
Macaque | zinc and ring finger 3 | 714156 | ||||||
Mouse | MGI:3039616 | 407821 | ||||||
Dog | zinc and ring finger 3 | VGNC:48840 | 486339 | |||||
Horse | zinc and ring finger 3 | VGNC:25402 | 100059173 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | zinc and ring finger 3 | |||||
Macaque | zinc and ring finger 3 | |||||
Mouse | ||||||
Dog | zinc and ring finger 3 | |||||
Horse | zinc and ring finger 3 | |||||
PMID | Year | Title |
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