You are using an outdated browser. Please upgrade your browser to improve your experience.

Tclin
KCNS2
Potassium voltage-gated channel subfamily S member 2

Protein Summary
Description
Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000287042
  • ENSP00000287042
  • ENSG00000156486
  • ENST00000521839
  • ENSP00000430712

Symbol
  • KIAA1144
  • KV9.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.99
molecular function
0.84
PubMedID
0.57
cell line
0.55
gene perturbation
0.53


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.76   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 170   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.76   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 170   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drugs: 3