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Tdark
ZNF490
Zinc finger protein 490

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000311437
  • ENSP00000311521
  • ENSG00000188033

Symbol
  • KIAA1198
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.76
histone modification site profile
0.71
tissue sample
0.7
tissue
0.69
cell line
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.37   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 79   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.37   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 79   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
1
15.9
body height
1
1
1
11.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
15.9
body height
1
11.3
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (32)
1 – 10 of 32
TRIM39
Tbio
Family: Enzyme
Novelty: 0.0837441
p_int: 0.998439379
p_ni: 0.001560621
Score: 0.201
Data Source: BioPlex,STRINGDB
RPL36AL
Tbio
Novelty: 0.09336423
p_int: 0.990050262
p_ni: 0.009949737
p_wrong: 1e-9
Data Source: BioPlex
EEF1A2
Tchem
Novelty: 0.001472
p_int: 0.947445094
p_ni: 0.052554906
Data Source: BioPlex
TOMM34
Tbio
Novelty: 0.05433718
p_int: 0.906485048
p_ni: 0.093216765
p_wrong: 0.000298187
Score: 0.206
Data Source: BioPlex,STRINGDB
PRDM15
Tbio
Family: TF; Epigenetic
Novelty: 0.17392284
p_int: 0.895366594
p_ni: 0.104633035
p_wrong: 3.72e-7
Score: 0.214
Data Source: BioPlex,STRINGDB
NEMF
Tbio
Novelty: 0.05052246
p_int: 0.893632549
p_ni: 0.106367451
Score: 0.187
Data Source: BioPlex,STRINGDB
RPL26L1
Tdark
Novelty: 0.75408617
p_int: 0.798932529
p_ni: 0.201067471
Data Source: BioPlex
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.913
Data Source: STRINGDB
BLOC1S5
Tbio
Novelty: 0.17565466
Score: 0.724
Data Source: STRINGDB
BLOC1S2
Tbio
Novelty: 0.02346362
Score: 0.705
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.37

PubMed score by year
PubTator Score  0.35

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer