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Tdark
PRR12
Proline-rich protein 12

Protein Summary
Description
This gene encodes a proline-rich protein that contains two A-T hook DNA binding domains. A chromosomal translocation and gene fusion between this gene and zinc finger, MIZ-type containing 1 (Gene ID: 57178) may underlie intellectual disability and neuropsychiatric problems in a human patient. Enriched expression of this gene in embryonic mouse brain suggests that this gene may play a role in nervous system development. [provided by RefSeq, Jul 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000418929
  • ENSP00000394510
  • ENSG00000126464
  • ENST00000615927
  • ENSP00000478000

Symbol
  • KIAA1205
  • KIAA1205
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.72
cell type or tissue
0.71
drug perturbation
0.71
tissue sample
0.62
cell line
0.57


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.87   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 13   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.87   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 13   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (5)
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (57)
1 – 10 of 57
ARHGAP12
Tbio
Family: Enzyme
Novelty: 0.162065
p_int: 0.99973955
p_ni: 0.000007259
p_wrong: 0.000253191
Data Source: BioPlex
SCAF1
Tbio
Novelty: 0.30651341
Score: 0.909
Data Source: STRINGDB
PRRG2
Tdark
Novelty: 0.25531915
Score: 0.857
Data Source: STRINGDB
IMMP1L
Tdark
Family: Enzyme
Novelty: 0.217337
Score: 0.714
Data Source: STRINGDB
MPPED2
Tbio
Family: Enzyme
Novelty: 0.12686905
Score: 0.707
Data Source: STRINGDB
BCL2L12
Tbio
Novelty: 0.02090982
Score: 0.706
Data Source: STRINGDB
RCN1
Tbio
Novelty: 0.00545832
Score: 0.694
Data Source: STRINGDB
TP53BP1
Tbio
Family: Epigenetic
Novelty: 0.0017892
Score: 0.673
Data Source: STRINGDB
INAFM1
Tdark
Novelty: 0.52173913
Score: 0.659
Data Source: STRINGDB
NOSIP
Tbio
Family: Enzyme
Novelty: 0.07771759
Score: 0.656
Data Source: STRINGDB
Publication Statistics
PubMed Score  6.87

PubMed score by year
PubTator Score  2.67

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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